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Target
Alpha-synuclein
Ligand
BDBM50544151
Substrate
n/a
Meas. Tech.
ChEMBL_1991810 (CHEMBL4625545)
IC50
1220±n/a nM
Citation
 Chen, L; Huang, GL; Lü, MH; Zhang, YX; Xu, J; Bai, SP Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro ?-synuclein aggregation. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50544151
Synonyms:
CHEMBL4640362
Type:
Small organic molecule
Emp. Form.:
C20H18N2O6S
Mol. Mass.:
414.432
SMILES:
Cc1ccc(cc1)S(=O)(=O)Nc1ccc(NC(=O)c2cc(O)c(O)c(O)c2)cc1
Structure:
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