Reaction Details Report a problem with these data
Target
P2X purinoceptor 1
Ligand
BDBM50064803
Substrate
n/a
Meas. Tech.
ChEMBL_147431 (CHEMBL754463)
EC50
5900±n/a nM
Citation
 Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem 44:340-9 (2001) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
ATP receptor | P2RX1_RAT | P2X1 | P2rx1 | Purinergic receptor | Purinergic, P2X1 | RP-2 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44969.95
Organism:
RAT
Description:
Purinergic, P2X1 0 RAT::P47824
Residue:
399
Sequence:
MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSDLISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIVTPQQTQGHCAENPEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKIQHPLCPVFNLGYVVRESGQDFRSLAEKGGVVGITIDWKCDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQNGTNRRHLFKVFGIHFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGEGEHDPVATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50064803
Synonyms:
3-Methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda*5*-phospha-benzocycloheptene-4,7-diol | CHEMBL74121 | MRS 2220
Type:
Small organic molecule
Emp. Form.:
C8H10NO5P
Mol. Mass.:
231.1425
SMILES:
Cc1ncc2COP(O)(=O)OCc2c1O
Structure:
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