Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50102303
Substrate
n/a
Meas. Tech.
ChEMBL_147891 (CHEMBL884926)
IC50
100000±n/a nM
Citation
 Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem 44:340-9 (2001) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50102303
Synonyms:
4-Chloro-3-(5-hydroxy-6-methyl-3,4-bis-phosphonooxymethyl-pyridin-2-ylazo)-benzenesulfonic acid | CHEMBL331238
Type:
Small organic molecule
Emp. Form.:
C14H16ClN3O12P2S
Mol. Mass.:
547.755
SMILES:
Cc1nc(N=Nc2cc(ccc2Cl)S(O)(=O)=O)c(COP(O)(O)=O)c(COP(O)(O)=O)c1O |w:4.3|
Structure:
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