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Target
Tubulin alpha-1A chain
Ligand
BDBM50012666
Substrate
n/a
Meas. Tech.
ChEMBL_212006 (CHEMBL815106)
IC50
5000±n/a nM
Citation
 Xia, Y; Yang, ZY; Xia, P; Hackl, T; Hamel, E; Mauger, A; Wu, JH; Lee, KH Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents. J Med Chem 44:3932-6 (2001) [PubMed]  Article 
Target
Name:
Tubulin alpha-1A chain
Synonyms:
TBA1A_PIG | TUBA1A | Tubulin | Tubulin alpha chain | Tubulin alpha-1A chain
Type:
Protein
Mol. Mass.:
50049.25
Organism:
Sus scrofa (Pig)
Description:
P02550
Residue:
451
Sequence:
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
  
Inhibitor
Name:
BDBM50012666
Synonyms:
2-((E)-Styryl)-3H-quinazolin-4-one | 2-Styryl-3H-quinazolin-4-one | CHEMBL47360
Type:
Small organic molecule
Emp. Form.:
C16H12N2O
Mol. Mass.:
248.2793
SMILES:
O=c1[nH]c(C=Cc2ccccc2)nc2ccccc12 |w:5.5|
Structure:
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