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Target
Papain
Ligand
BDBM50107000
Substrate
n/a
Meas. Tech.
ChEBML_152640
IC50
23000±n/a nM
Citation
 Singh, SB; Graham, PL; Reamer, RA; Cordingley, MG Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorg Med Chem Lett 11:3143-6 (2001) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50107000
Synonyms:
6-Acetyl-5-hydroxy-2-methoxy-7-methyl-[1,4]naphthoquinone | CHEMBL322776
Type:
Small organic molecule
Emp. Form.:
C14H12O5
Mol. Mass.:
260.2421
SMILES:
COC1=CC(=O)c2c(O)c(C(C)=O)c(C)cc2C1=O |t:2|
Structure:
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