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Target
Papain
Ligand
BDBM50107007
Substrate
n/a
Meas. Tech.
ChEBML_152640
IC50
33000±n/a nM
Citation
 Singh, SB; Graham, PL; Reamer, RA; Cordingley, MG Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorg Med Chem Lett 11:3143-6 (2001) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50107007
Synonyms:
Acetic acid 2-acetyl-6-methoxy-3-methyl-5,8-dioxo-5,8-dihydro-naphthalen-1-yl ester | CHEMBL104123
Type:
Small organic molecule
Emp. Form.:
C16H14O6
Mol. Mass.:
302.2788
SMILES:
COC1=CC(=O)c2c(OC(C)=O)c(C(C)=O)c(C)cc2C1=O |t:2|
Structure:
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