Reaction Details Report a problem with these data
Target
Melanocortin receptor 3
Ligand
BDBM50111165
Substrate
n/a
Meas. Tech.
ChEBML_106022
Ki
58000±n/a nM
Citation
 Mutulis, F; Mutule, I; Lapins, M; Wikberg, JE Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors. Bioorg Med Chem Lett 12:1035-8 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM50111165
Synonyms:
CHEMBL266305 | N-(2-Amino-ethyl)-2,3-bis-[(naphthalen-2-ylmethyl)-amino]-propionamide
Type:
Small organic molecule
Emp. Form.:
C27H30N4O
Mol. Mass.:
426.5533
SMILES:
NCCNC(=O)[C@H](CNCc1ccc2ccccc2c1)NCc1ccc2ccccc2c1
Structure:
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