Reaction Details Report a problem with these data
Target
Melanocortin receptor 3
Ligand
BDBM50111160
Substrate
n/a
Meas. Tech.
ChEBML_106022
Ki
59000±n/a nM
Citation
 Mutulis, F; Mutule, I; Lapins, M; Wikberg, JE Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors. Bioorg Med Chem Lett 12:1035-8 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM50111160
Synonyms:
CHEMBL8045 | [2-(1H-Indol-3-yl)-ethyl]-naphthalen-2-ylmethyl-amine
Type:
Small organic molecule
Emp. Form.:
C21H20N2
Mol. Mass.:
300.3969
SMILES:
C(Cc1c[nH]c2ccccc12)NCc1ccc2ccccc2c1
Structure:
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