Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50111156
Substrate
n/a
Meas. Tech.
ChEBML_106361
Ki
27000±n/a nM
Citation
 Mutulis, F; Mutule, I; Lapins, M; Wikberg, JE Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors. Bioorg Med Chem Lett 12:1035-8 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50111156
Synonyms:
CHEMBL269776 | N-(3-Amino-propyl)-3-[(1H-indol-3-ylmethyl)-amino]-2-[(naphthalen-2-ylmethyl)-amino]-propionamide
Type:
Small organic molecule
Emp. Form.:
C26H31N5O
Mol. Mass.:
429.5572
SMILES:
NCCCNC(=O)[C@H](CNCc1c[nH]c2ccccc12)NCc1ccc2ccccc2c1
Structure:
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