Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM50553255
Substrate
n/a
Meas. Tech.
ChEMBL_2045853 (CHEMBL4700552)
IC50
190±n/a nM
Citation
 Oliveri, V Toward the discovery and development of effective modulators of ?-synuclein amyloid aggregation. Eur J Med Chem 167:10-36 (2019) [PubMed]  Article 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50553255
Synonyms:
All-Trans-Retinal | CHEBI:17898 | Retinal
Type:
Small organic molecule
Emp. Form.:
C20H28O
Mol. Mass.:
284.4357
SMILES:
C\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=O |c:9|
Structure:
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