Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50114704
Substrate
n/a
Meas. Tech.
ChEMBL_105099 (CHEMBL714106)
Ki
40.6±n/a nM
Citation
 Wallez, V; Durieux-Poissonnier, S; Chavatte, P; Boutin, JA; Audinot, V; Nicolas, JP; Bennejean, C; Delagrange, P; Renard, P; Lesieur, D Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands. J Med Chem 45:2788-800 (2002) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50114704
Synonyms:
CHEMBL33549 | N-(2-(5-methoxy-2-(3-methoxybenzyl)benzofuran-3-yl)ethyl)acetamide | N-{2-[5-Methoxy-2-(3-methoxy-benzyl)-benzofuran-3-yl]-ethyl}-acetamide
Type:
Small organic molecule
Emp. Form.:
C21H23NO4
Mol. Mass.:
353.4116
SMILES:
COc1cccc(Cc2oc3ccc(OC)cc3c2CCNC(C)=O)c1
Structure:
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