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Target
Phosphoglycerate mutase 1
Ligand
BDBM50557320
Substrate
n/a
Meas. Tech.
ChEMBL_2058835 (CHEMBL4713836)
IC50
3400±n/a nM
Citation
 Jiang, K; Gao, B; Yu, J; Jiang, L; Niu, A; Jia, Y; Meng, T; Zhou, L; Wang, J Design, synthesis, and biological evaluation of 1,3,6,7-tetrahydroxyxanthone derivatives as phosphoglycerate mutase 1 inhibitors. Bioorg Med Chem Lett 36:0 (2021) [PubMed]  Article 
Target
Name:
Phosphoglycerate mutase 1
Synonyms:
BPG-dependent PGAM 1 | PGAM-B | PGAM1 | PGAM1_HUMAN | PGAMA | Phosphoglycerate mutase 1 | Phosphoglycerate mutase isozyme B
Type:
PROTEIN
Mol. Mass.:
28806.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109479
Residue:
254
Sequence:
MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK
  
Inhibitor
Name:
BDBM50557320
Synonyms:
CHEMBL519864
Type:
Small organic molecule
Emp. Form.:
C18H16O6
Mol. Mass.:
328.316
SMILES:
[#6]\[#6](-[#6])=[#6]/[#6]-c1c(-[#8])c(-[#8])cc2oc3cc(-[#8])cc(-[#8])c3c(=O)c12
Structure:
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