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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM15613
Substrate
n/a
Meas. Tech.
ChEMBL_2058917 (CHEMBL4713918)
Ki
7660±n/a nM
Citation
 Salgin-Goksen, U; Telli, G; Erikci, A; Dedecengiz, E; Tel, BC; Kaynak, FB; Yelekci, K; Ucar, G; Gokhan-Kelekci, N New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors. J Med Chem 64:1989-2009 (2021) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM15613
Synonyms:
4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide | Aurorix | CHEMBL86304 | MCL | Moclobemide
Type:
Small organic molecule
Emp. Form.:
C13H17ClN2O2
Mol. Mass.:
268.739
SMILES:
Clc1ccc(cc1)C(=O)NCCN1CCOCC1
Structure:
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