Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50553885
Substrate
n/a
Meas. Tech.
ChEMBL_2067376 (CHEMBL4722629)
Kd
3630±n/a nM
Citation
 Xiao, Z; Fokkens, M; Chen, D; Kok, T; Proietti, G; van Merkerk, R; Poelarends, GJ; Dekker, FJ Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem 186:0 (2020) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50553885
Synonyms:
CHEMBL4745151
Type:
Small organic molecule
Emp. Form.:
C18H14FN5O2
Mol. Mass.:
351.3345
SMILES:
Oc1ccc(cc1F)-n1cc(CNC(=O)c2cc3ccccc3[nH]2)nn1
Structure:
Search PDB for entries with ligand similarity: