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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50121412
Substrate
n/a
Meas. Tech.
ChEBML_154362
Ki
2200±n/a nM
Citation
 Thor, M; Beierlein, K; Dykes, G; Gustavsson, AL; Heidrich, J; Jendeberg, L; Lindqvist, B; Pegurier, C; Roussel, P; Slater, M; Svensson, S; Sydow-Bäckman, M; Thornström, U; Uppenberg, J Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators. Bioorg Med Chem Lett 12:3565-7 (2002) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50121412
Synonyms:
2-(2,4-Dichloro-benzoylamino)-5-methyl-benzoic acid | CHEMBL118972
Type:
Small organic molecule
Emp. Form.:
C15H11Cl2NO3
Mol. Mass.:
324.159
SMILES:
Cc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(c1)C(O)=O
Structure:
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