Reaction Details Report a problem with these data
Target
Calpain small subunit 1
Ligand
BDBM50124031
Substrate
n/a
Meas. Tech.
ChEMBL_43863 (CHEMBL658523)
Ki
540±n/a nM
Citation
 Donkor, IO; Korukonda, R; Huang, TL; LeCour, L Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics. Bioorg Med Chem Lett 13:783-4 (2003) [PubMed]  Article 
Target
Name:
Calpain small subunit 1
Synonyms:
CANP small subunit | CAPN4 | CAPNS1 | CDPS | CPNS1_PIG | CSS1 | Calcium-activated neutral proteinase small subunit | Calcium-dependent protease small subunit | Calcium-dependent protease small subunit 1 | Calpain regulatory subunit
Type:
PROTEIN
Mol. Mass.:
28062.13
Organism:
Sus scrofa
Description:
ChEMBL_43862
Residue:
266
Sequence:
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFDVDRSGTIGSSELPGAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
  
Inhibitor
Name:
BDBM50124031
Synonyms:
1-(Toluene-4-sulfonyl)-piperidine-2-carboxylic acid (1-benzyl-2-oxo-ethyl)-amide | CHEMBL163790
Type:
Small organic molecule
Emp. Form.:
C22H26N2O4S
Mol. Mass.:
414.518
SMILES:
Cc1ccc(cc1)S(=O)(=O)N1CCCCC1C(=O)NC(Cc1ccccc1)C=O
Structure:
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