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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50127934
Substrate
n/a
Meas. Tech.
ChEBML_154546
IC50
>10000±n/a nM
Citation
 Koyama, H; Boueres, JK; Han, W; Metzger, EJ; Bergman, JP; Gratale, DF; Miller, DJ; Tolman, RL; MacNaul, KL; Berger, JP; Doebber, TW; Leung, K; Moller, DE; Heck, JV; Sahoo, SP 5-Aryl thiazolidine-2,4-diones as selective PPARgamma agonists. Bioorg Med Chem Lett 13:1801-4 (2003) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50127934
Synonyms:
5-{3-Methoxy-4-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy]-phenyl}-thiazolidine-2,4-dione | CHEMBL50755
Type:
Small organic molecule
Emp. Form.:
C28H29NO6S
Mol. Mass.:
507.598
SMILES:
CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1OC)-c1sc(=O)[nH]c1O
Structure:
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