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Target
Atypical chemokine receptor 3
Ligand
BDBM50567151
Substrate
n/a
Meas. Tech.
ChEMBL_2102410 (CHEMBL4810806)
Ki
155±n/a nM
Citation
 Aspnes, GE; Menhaji-Klotz, E; Boehm, M; Londregan, AT; Lee, ECY; Limberakis, C; Coffey, SB; Brown, JA; Jones, RM; Hesp, KD Discovery and evaluation of non-basic small molecule modulators of the atypical chemokine receptor CXCR7. Bioorg Med Chem Lett 50:0 (2021) [PubMed]  Article 
Target
Name:
Atypical chemokine receptor 3
Synonyms:
ACKR3_MOUSE | Ackr3 | Atypical chemokine receptor 3 | C-X-C chemokine receptor type 7 | CXC-R7 | CXCR-7 | Chemokine orphan receptor 1 | Cmkor1 | Cxcr7 | G-protein coupled receptor RDC1 homolog | RDC-1 | Rdc1
Type:
PROTEIN
Mol. Mass.:
41640.48
Organism:
Mus musculus
Description:
ChEMBL_117401
Residue:
362
Sequence:
MDVHLFDYAEPGNYSDINWPCNSSDCIVVDTVQCPTMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVITIPVWVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTGTSSYKKKMVRRVVCILVWLLAFFVSLPDTYYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVILGFAVPFTIIAIFYFLLARAMSASGDQEKHSSRKIIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTCQLENVLFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQNTK
  
Inhibitor
Name:
BDBM50567151
Synonyms:
CHEMBL4848754
Type:
Small organic molecule
Emp. Form.:
C20H27N7O2
Mol. Mass.:
397.4741
SMILES:
[H][C@@]12CN(C[C@]1([H])[C@H]2C(=O)N[C@H]1CCN(C1)c1nccn2ccnc12)C(=O)N(C)CC |r|
Structure:
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