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Target
D(2) dopamine receptor
Ligand
BDBM50026553
Substrate
n/a
Meas. Tech.
ChEMBL_62879 (CHEMBL878289)
Ki
3±n/a nM
Citation
 Venhuis, BJ; Dijkstra, D; Wustrow, D; Meltzer, LT; Wise, LD; Johnson, SJ; Wikström, HV Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity. J Med Chem 46:4136-40 (2003) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50026553
Synonyms:
(+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | (+/-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | (-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol (DP-5,6-ADTN) | CHEMBL11845
Type:
Small organic molecule
Emp. Form.:
C16H25NO2
Mol. Mass.:
263.3752
SMILES:
CCCN(CCC)C1CCc2c(C1)ccc(O)c2O
Structure:
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