Reaction Details Report a problem with these data
Target
P2Y purinoceptor 14
Ligand
BDBM50569006
Substrate
n/a
Meas. Tech.
ChEMBL_2107299 (CHEMBL4815974)
IC50
3.0±n/a nM
Citation
 Lu, R; Wang, Y; Liu, C; Zhang, Z; Li, B; Meng, Z; Jiang, C; Hu, Q Design, synthesis and evaluation of 3-amide-5-aryl benzoic acid derivatives as novel P2Y Eur J Med Chem 216:0 (2021) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50569006
Synonyms:
CHEMBL4875670
Type:
Small organic molecule
Emp. Form.:
C20H18N2O4
Mol. Mass.:
350.3679
SMILES:
Cc1noc(C)c1-c1cc(NC(=O)c2ccc(C)cc2)cc(c1)C(O)=O
Structure:
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