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Target
Matrix metalloproteinase-26
Ligand
BDBM50137277
Substrate
n/a
Meas. Tech.
ChEBML_104566
IC50
492±n/a nM
Citation
 Ma, D; Wu, W; Yang, G; Li, J; Li, J; Ye, Q Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett 14:47-50 (2003) [PubMed]  Article 
Target
Name:
Matrix metalloproteinase-26
Synonyms:
Endometase | MMP-26 | MMP26 | MMP26_HUMAN | Matrilysin-2 | Matrix metalloproteinase 26 | Matrix metalloproteinase-26
Type:
PROTEIN
Mol. Mass.:
29707.55
Organism:
Homo sapiens (Human)
Description:
ChEMBL_806653
Residue:
261
Sequence:
MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYGEKCSSDIP
  
Inhibitor
Name:
BDBM50137277
Synonyms:
2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide | CHEMBL148406
Type:
Small organic molecule
Emp. Form.:
C16H17N3O5S
Mol. Mass.:
363.388
SMILES:
Nc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO
Structure:
Search PDB for entries with ligand similarity: