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Target
Matrix metalloproteinase-26
Ligand
BDBM50137287
Substrate
n/a
Meas. Tech.
ChEBML_104566
IC50
1453±n/a nM
Citation
 Ma, D; Wu, W; Yang, G; Li, J; Li, J; Ye, Q Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett 14:47-50 (2003) [PubMed]  Article 
Target
Name:
Matrix metalloproteinase-26
Synonyms:
Endometase | MMP-26 | MMP26 | MMP26_HUMAN | Matrilysin-2 | Matrix metalloproteinase 26 | Matrix metalloproteinase-26
Type:
PROTEIN
Mol. Mass.:
29707.55
Organism:
Homo sapiens (Human)
Description:
ChEMBL_806653
Residue:
261
Sequence:
MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQFHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDIQRIQHLYGEKCSSDIP
  
Inhibitor
Name:
BDBM50137287
Synonyms:
2-Benzenesulfonyl-6-benzyloxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide | 6-(benzyloxy)-N-hydroxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide | CHEMBL147881
Type:
Small organic molecule
Emp. Form.:
C23H22N2O5S
Mol. Mass.:
438.496
SMILES:
ONC(=O)C1N(CCc2cc(OCc3ccccc3)ccc12)S(=O)(=O)c1ccccc1
Structure:
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