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Target
Cathepsin G
Ligand
BDBM50139743
Substrate
n/a
Meas. Tech.
ChEMBL_45351 (CHEMBL661888)
IC50
1300±n/a nM
Citation
 Maryanoff, BE Inhibitors of serine proteases as potential therapeutic agents: the road from thrombin to tryptase to cathepsin G. J Med Chem 47:769-87 (2004) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50139743
Synonyms:
(2-{3-[Methyl-(phenethylcarbamoyl-methyl)-carbamoyl]-naphthalen-2-yl}-1-naphthalen-1-yl-2-oxo-ethyl)-phosphonic acid | CHEMBL163831
Type:
Small organic molecule
Emp. Form.:
C34H31N2O6P
Mol. Mass.:
594.5935
SMILES:
CN(CC(=O)NCCc1ccccc1)C(=O)c1cc2ccccc2cc1C(=O)C(c1cccc2ccccc12)P(O)(O)=O
Structure:
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