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Target
Baculoviral IAP repeat-containing protein 5
Ligand
BDBM50573761
Substrate
n/a
Meas. Tech.
ChEMBL_2120696 (CHEMBL4829843)
Kd
4270±n/a nM
Citation
 Albadari, N; Deng, S; Chen, H; Zhao, G; Yue, J; Zhang, S; Miller, DD; Wu, Z; Li, W Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold. Eur J Med Chem 224:0 (2021) [PubMed]  Article 
Target
Name:
Baculoviral IAP repeat-containing protein 5
Synonyms:
API4 | Apoptosis inhibitor 4 | Apoptosis inhibitor survivin | BIRC5 | BIRC5_HUMAN | IAP4
Type:
PROTEIN
Mol. Mass.:
16386.52
Organism:
Homo sapiens (Human)
Description:
ChEMBL_443470
Residue:
142
Sequence:
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD
  
Inhibitor
Name:
BDBM50573761
Synonyms:
CHEMBL4862376
Type:
Small organic molecule
Emp. Form.:
C25H24F3N5O
Mol. Mass.:
467.4862
SMILES:
Oc1c(CN2CCCCC2)cc(Cn2ncc(n2)-c2ccc(cc2)C(F)(F)F)c2cccnc12
Structure:
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