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Target
Interleukin-2
Ligand
BDBM50575319
Substrate
n/a
Meas. Tech.
ChEMBL_2124819 (CHEMBL4834052)
Kd
420±n/a nM
Citation
 Gironda-Martínez, A; Gorre, ÉMD; Prati, L; Gosalbes, JF; Dakhel, S; Cazzamalli, S; Samain, F; Donckele, EJ; Neri, D Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries. J Med Chem 64:17496-17510 (2021) [PubMed]  Article 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM50575319
Synonyms:
CHEMBL4869829
Type:
Small organic molecule
Emp. Form.:
C18H15IN2O4
Mol. Mass.:
450.2272
SMILES:
OC(=O)[C@H](Cc1ccc(O)c(I)c1)NC(=O)c1cc2ccccc2[nH]1 |r|
Structure:
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