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Target
NAD-dependent protein deacylase sirtuin-5, mitochondrial
Ligand
BDBM50576715
Substrate
n/a
Meas. Tech.
ChEMBL_2127692 (CHEMBL4837037)
Ki
122000±n/a nM
Citation
 Zhou, Y; Shen, W; Peng, J; Deng, Y; Li, X Identification of isoform/domain-selective fragments from the selection of DNA-encoded dynamic library. Bioorg Med Chem 45:0 (2021) [PubMed]  Article 
Target
Name:
NAD-dependent protein deacylase sirtuin-5, mitochondrial
Synonyms:
NAD-dependent protein deacetylase sirtuin-5 (SIRT5) | NAD-dependent protein deacylase sirtuin-5, mitochondrial | Regulatory protein SIR2 homolog 5 | SIR2-like protein 5 | SIR2L5 | SIR5_HUMAN | SIRT5
Type:
Protein
Mol. Mass.:
33892.62
Organism:
Homo sapiens (Human)
Description:
Q9NXA8
Residue:
310
Sequence:
MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALACHENETVS
  
Inhibitor
Name:
BDBM50576715
Synonyms:
CHEMBL4870282
Type:
Small organic molecule
Emp. Form.:
C39H52N4O4
Mol. Mass.:
640.8546
SMILES:
CN(CCCN1c2ccccc2CCc2ccccc12)C(=O)CCCCCNC(=O)C[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C |r|
Structure:
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