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Target
Sodium- and chloride-dependent creatine transporter 1
Ligand
BDBM50119791
Substrate
n/a
Meas. Tech.
ChEBML_49276
Ki
27000±n/a nM
Citation
 Crooks, PA; Ayers, JT; Xu, R; Sumithran, SP; Grinevich, VP; Wilkins, LH; Deaciuc, AG; Allen, DD; Dwoskin, LP Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release. Bioorg Med Chem Lett 14:1869-74 (2004) [PubMed]  Article 
Target
Name:
Sodium- and chloride-dependent creatine transporter 1
Synonyms:
CHOT1 | CT1 | Creatine transporter | Creatine transporter 1 | SC6A8_RAT | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Solute carrier family 6 member 8
Type:
PROTEIN
Mol. Mass.:
70632.63
Organism:
Rattus norvegicus
Description:
ChEMBL_49276
Residue:
635
Sequence:
MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYKPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
  
Inhibitor
Name:
BDBM50119791
Synonyms:
1-Decyl-3-((S)-1-methyl-pyrrolidin-2-yl)-pyridinium; iodide | 1-Decyl-3-(1-methyl-pyrrolidin-2-yl)-pyridine;iodide | CHEMBL56296
Type:
Small organic molecule
Emp. Form.:
C20H35N2
Mol. Mass.:
303.5048
SMILES:
CCCCCCCCCC[n+]1cccc(c1)[C@@H]1CCCN1C
Structure:
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