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Target
Adenosine receptor A3
Ligand
BDBM50145229
Substrate
n/a
Meas. Tech.
ChEBML_31841
IC50
490±n/a nM
Citation
 Okamura, T; Kurogi, Y; Hashimoto, K; Nishikawa, H; Nagao, Y Facile synthesis of fused 1,2,4-triazolo[1,5-c]pyrimidine derivatives as human adenosine A3 receptor ligands. Bioorg Med Chem Lett 14:2443-6 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50145229
Synonyms:
5-Butyl-2-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-c]quinazoline | CHEMBL125288
Type:
Small organic molecule
Emp. Form.:
C20H17F3N4
Mol. Mass.:
370.371
SMILES:
CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(cc1)C(F)(F)F
Structure:
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