Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50152213
Substrate
n/a
Meas. Tech.
ChEMBL_303573 (CHEMBL828973)
Ki
12±n/a nM
Citation
 Vu, CB; Pan, D; Peng, B; Sha, L; Kumaravel, G; Jin, X; Phadke, D; Engber, T; Huang, C; Reilly, J; Tam, S; Petter, RC Studies on adenosine A2a receptor antagonists: comparison of three core heterocycles. Bioorg Med Chem Lett 14:4831-4 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50152213
Synonyms:
2-Furan-2-yl-N*5*-methyl-N*5*-[(R)-1-(5-methyl-isoxazol-3-ylmethyl)-pyrrolidin-2-ylmethyl]-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine | CHEMBL353323
Type:
Small organic molecule
Emp. Form.:
C19H23N9O2
Mol. Mass.:
409.445
SMILES:
CN(C[C@H]1CCCN1Cc1cc(C)on1)c1nc(N)n2nc(nc2n1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: