Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50152507
Substrate
n/a
Meas. Tech.
ChEMBL_303623 (CHEMBL828834)
Ki
10±n/a nM
Citation
 Torisu, K; Kobayashi, K; Iwahashi, M; Nakai, Y; Onoda, T; Nagase, T; Sugimoto, I; Okada, Y; Matsumoto, R; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 14:4891-5 (2004) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_MOUSE | Prostanoid DP receptor | Ptgdr
Type:
PROTEIN
Mol. Mass.:
40018.63
Organism:
Mus musculus
Description:
ChEMBL_788408
Residue:
357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
  
Inhibitor
Name:
BDBM50152507
Synonyms:
CHEMBL182555 | [1-(4-Butoxy-benzoyl)-2-methyl-1H-indol-4-yl]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C22H23NO4
Mol. Mass.:
365.4223
SMILES:
CCCCOc1ccc(cc1)C(=O)n1c(C)cc2c(CC(O)=O)cccc12
Structure:
Search PDB for entries with ligand similarity: