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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50153526
Substrate
n/a
Meas. Tech.
ChEMBL_305604 (CHEMBL828142)
IC50
32400.0±n/a nM
Citation
 Myers, AC; Kowalski, JA; Lipton, MA Facile incorporation of urea pseudopeptides into protease substrate analogue inhibitors. Bioorg Med Chem Lett 14:5219-22 (2004) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50153526
Synonyms:
(S)-2-{2-[(S)-2-((R)-3-{1-[2-((S)-2-Amino-propionylamino)-propionylamino]-2-phenyl-ethyl}-ureido)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester | CHEMBL187239
Type:
Small organic molecule
Emp. Form.:
C35H51N7O7
Mol. Mass.:
681.8221
SMILES:
COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)N[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)N)C(C)C)C(C)C
Structure:
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