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Target
C-C motif chemokine 2
Ligand
BDBM50585055
Substrate
n/a
Meas. Tech.
ChEMBL_2161474 (CHEMBL5046335)
Kd
1670±n/a nM
Citation
 Shanthamurthy, CD; Leviatan Ben-Arye, S; Kumar, NV; Yehuda, S; Amon, R; Woods, RJ; Padler-Karavani, V; Kikkeri, R Heparan Sulfate Mimetics Differentially Affect Homologous Chemokines and Attenuate Cancer Development. J Med Chem 64:3367-3380 (2021) [PubMed]  Article 
Target
Name:
C-C motif chemokine 2
Synonyms:
CCL2 | CCL2_HUMAN | HC11 | MCAF | MCP-1 | MCP1 | Monocyte chemoattractant protein 1 | Monocyte chemotactic and activating factor | Monocyte chemotactic protein 1 | Monocyte secretory protein JE | SCYA2 | Small-inducible cytokine A2
Type:
PROTEIN
Mol. Mass.:
11032.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1363188
Residue:
99
Sequence:
MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT
  
Inhibitor
Name:
BDBM50585055
Synonyms:
CHEMBL5081237
Type:
Small organic molecule
Emp. Form.:
C28H43NO41S5
Mol. Mass.:
1209.948
SMILES:
[H][C@@]1(O[C@H]2[C@H](O)[C@@H](OS(O)(=O)=O)[C@H](OCCOCCN)O[C@H]2C(O)=O)O[C@H]([C@@H](O[C@]2([H])O[C@H]([C@@H](O[C@]3([H])O[C@H]([C@@H](OS(O)(=O)=O)[C@H](O)[C@H]3OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]2OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]1OS(O)(=O)=O)C(O)=O |r|
Structure:
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