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Target
Mu-type opioid receptor
Ligand
BDBM50154037
Substrate
n/a
Meas. Tech.
ChEMBL_310387 (CHEMBL834471)
EC50
1300±n/a nM
Citation
 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Rationale, design, and synthesis of novel phenyl imidazoles as opioid receptor agonists for gastrointestinal disorders. J Med Chem 47:5009-20 (2004) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50154037
Synonyms:
2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phenyl-1H-imidazol-2-yl)-pyrrolidin-1-yl]-propan-1-one | CHEMBL186527
Type:
Small organic molecule
Emp. Form.:
C23H26N4O2
Mol. Mass.:
390.4781
SMILES:
Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1
Structure:
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