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Target
Capsid protein
Ligand
BDBM50586541
Substrate
n/a
Meas. Tech.
ChEMBL_2169008 (CHEMBL5054067)
EC50
400±n/a nM
Citation
 Kuduk, SD; Stoops, B; Lam, AM; Espiritu, C; Vogel, R; Lau, V; Klumpp, K; Flores, OA; Hartman, GD Oxadiazepinone HBV capsid assembly modulators. Bioorg Med Chem Lett 52:0 (2021) [PubMed]  Article 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50586541
Synonyms:
CHEMBL5089525
Type:
Small organic molecule
Emp. Form.:
C15H16ClN5O3
Mol. Mass.:
349.772
SMILES:
CONC(=O)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Structure:
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