Reaction Details Report a problem with these data
Target
Histamine H2 receptor
Ligand
BDBM50586673
Substrate
n/a
Meas. Tech.
ChEMBL_2169496 (CHEMBL5054555)
Ki
33±n/a nM
Citation
 Tropmann, K; Seibel-Ehlert, U; Littmann, T; Strasser, A Shining light on the histamine H Bioorg Med Chem Lett 52:0 (2021) [PubMed]  Article 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40115.31
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
359
Sequence:
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
  
Inhibitor
Name:
BDBM50586673
Synonyms:
CHEMBL5092102
Type:
Small organic molecule
Emp. Form.:
C16H31N7O
Mol. Mass.:
337.4636
SMILES:
NCCCCCCCCNC(=O)\N=C(/N)NCCCc1c[nH]cn1
Structure:
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