Reaction Details Report a problem with these data
Target
Trypsin
Ligand
BDBM50157086
Substrate
n/a
Meas. Tech.
ChEMBL_302473 (CHEMBL826338)
Ki
480±n/a nM
Citation
 Bruncko, M; McClellan, WJ; Wendt, MD; Sauer, DR; Geyer, A; Dalton, CR; Kaminski, MA; Weitzberg, M; Gong, J; Dellaria, JF; Mantei, R; Zhao, X; Nienaber, VL; Stewart, K; Klinghofer, V; Bouska, J; Rockway, TW; Giranda, VL Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties. Bioorg Med Chem Lett 15:93-8 (2004) [PubMed]  Article 
Target
Name:
Trypsin
Synonyms:
TRYP_PIG
Type:
PROTEIN
Mol. Mass.:
24411.24
Organism:
Sus scrofa
Description:
ChEMBL_1450738
Residue:
231
Sequence:
FPTDDDDKIVGGYTCAANSIPYQVSLNSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
  
Inhibitor
Name:
BDBM50157086
Synonyms:
8-Bromo-6-styryl-naphthalene-2-carboxamidine | CHEMBL360703
Type:
Small organic molecule
Emp. Form.:
C19H15BrN2
Mol. Mass.:
351.24
SMILES:
NC(=N)c1ccc2cc(\C=C\c3ccccc3)cc(Br)c2c1
Structure:
Search PDB for entries with ligand similarity: