Reaction Details
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Transient receptor potential cation channel subfamily V member 2
Ligand
BDBM50318487
Substrate
n/a
Meas. Tech.
ChEMBL_2184546 (CHEMBL5096628)
IC50
1500±n/a nM
Citation
Sampson, PB Phytocannabinoid Pharmacology: Medicinal Properties of J Nat Prod 84:142-160 (2021) [PubMed] More Info.:
Target
Name:
Transient receptor potential cation channel subfamily V member 2
Synonyms:
OTRPC2 | Osm-9-like TRP channel 2 | TRPV2 | TRPV2_HUMAN | Transient receptor potential cation channel subfamily V member 2 | VRL | VRL-1 | Vanilloid receptor-like protein 1
Type:
PROTEIN
Mol. Mass.:
85972.07
Organism:
Homo sapiens
Description:
ChEMBL_101052
Residue:
764
Sequence:
MTSPSSSPVFRLETLDGGQEDGSEADRGKLDFGSGLPPMESQFQGEDRKFAPQIRVNLNYRKGTGASQPDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYGPVRVSLYDLASVDSCEENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLLIPKFFLNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGHILILLGGIYLLVGQLWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPLLVSALVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQEAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLLLLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRKKQRAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPSGAGVPRTLENPVLASPPKEDEDGASEENYVPVQLLQSN
Inhibitor
Name:
BDBM50318487
Synonyms:
CHEMBL497318 | Cannabigerol
Type:
Small organic molecule
Emp. Form.:
C21H32O2
Mol. Mass.:
316.4776
SMILES:
[#6]-[#6]-[#6]-[#6]-[#6]-c1cc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c1
Structure:
