Reaction Details Report a problem with these data
Target
Melanocortin receptor 3
Ligand
BDBM50160531
Substrate
n/a
Meas. Tech.
ChEMBL_302755 (CHEMBL838702)
Ki
630±n/a nM
Citation
 Tran, JA; Pontillo, J; Arellano, M; White, NS; Fleck, BA; Marinkovic, D; Tucci, FC; Lanier, M; Nelson, J; Saunders, J; Foster, AC; Chen, C Identification of agonists and antagonists of the human melanocortin-4 receptor from piperazinebenzylamines. Bioorg Med Chem Lett 15:833-7 (2005) [PubMed]  Article 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM50160531
Synonyms:
CHEMBL183799 | Quinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[1-(piperidin-3-ylamino)-ethyl]-phenyl}-piperazin-1-yl)-ethyl]-amide
Type:
Small organic molecule
Emp. Form.:
C36H41ClN6O2
Mol. Mass.:
625.203
SMILES:
CC(NC1CCCNC1)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)c1cnc2ccccc2c1
Structure:
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