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Target
D(1A) dopamine receptor
Ligand
BDBM50033116
Substrate
n/a
Meas. Tech.
ChEMBL_2201070 (CHEMBL5113778)
Ki
3.9±n/a nM
Citation
 Zhao, Z; Kang, K; Yue, J; Ji, X; Qiao, H; Fan, P; Zheng, X Research progress in biological activities of isochroman derivatives. Eur J Med Chem 210:0 (2021) [PubMed] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50033116
Synonyms:
(1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol | A-77636 | CHEMBL291143 | cid_6603703
Type:
Small organic molecule
Emp. Form.:
C20H27NO3
Mol. Mass.:
329.4333
SMILES:
NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C12CC3CC(CC(C3)C1)C2 |TLB:21:16:23:22.20.19,21:20:23:15.16.17,THB:19:18:15:22.20.21,19:20:15:23.18.17|
Structure:
Search PDB for entries with ligand similarity: