Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM50119380
Substrate
n/a
Meas. Tech.
ChEMBL_302994 (CHEMBL830233)
Ki
636±n/a nM
Citation
 Ding, K; Chen, J; Ji, M; Wu, X; Varady, J; Yang, CY; Lu, Y; Deschamps, JR; Levant, B; Wang, S Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands. J Med Chem 48:3171-81 (2005) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(1B) dopamine receptor | DOPAMINE D5 | DRD5_RAT | Dopamine D1B | Dopamine D5 receptor | Dopamine receptor | Drd5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52827.88
Organism:
RAT
Description:
Dopamine D1B 0 RAT::P25115
Residue:
475
Sequence:
MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
  
Inhibitor
Name:
BDBM50119380
Synonyms:
CHEMBL25236 | CHEMBL540612 | N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide | Naphthalene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Type:
Small organic molecule
Emp. Form.:
C26H31N3O2
Mol. Mass.:
417.5432
SMILES:
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1
Structure:
Search PDB for entries with ligand similarity: