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Target
NEDD8-conjugating enzyme Ubc12
Ligand
BDBM50311743
Substrate
n/a
Meas. Tech.
ChEMBL_2214856 (CHEMBL5127988)
IC50
10330±n/a nM
Citation
 Liang, Q; Liu, M; Li, J; Tong, R; Hu, Y; Bai, L; Shi, J NAE modulators: A potential therapy for gastric carcinoma. Eur J Med Chem 231:0 (2022) [PubMed] 
Target
Name:
NEDD8-conjugating enzyme Ubc12
Synonyms:
2.3.2.- | NEDD8 carrier protein | NEDD8-conjugating enzyme Ubc12 | UBC12 | UBC12_HUMAN | UBE2M | Ubiquitin-conjugating enzyme E2 M
Type:
PROTEIN
Mol. Mass.:
20901.74
Organism:
Homo sapiens
Description:
ChEMBL_118032
Residue:
183
Sequence:
MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK
  
Inhibitor
Name:
BDBM50311743
Synonyms:
CHEMBL487992 | GARTANIN
Type:
Small organic molecule
Emp. Form.:
C23H24O6
Mol. Mass.:
396.4331
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2oc3c(-[#8])ccc(-[#8])c3c(=O)c2c1-[#8]
Structure:
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