Reaction Details Report a problem with these data
Target
Cytochrome c oxidase subunit 2
Ligand
BDBM50595004
Substrate
n/a
Meas. Tech.
ChEMBL_2215097 (CHEMBL5128229)
IC50
8600±n/a nM
Citation
 Fantacuzzi, M; Amoroso, R; Carradori, S; De Filippis, B Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy. Eur J Med Chem 233:0 (2022) [PubMed] 
Target
Name:
Cytochrome c oxidase subunit 2
Synonyms:
COII | COX2 | COX2_HUMAN | COXII | MT-CO2 | MTCO2
Type:
PROTEIN
Mol. Mass.:
25555.66
Organism:
Homo sapiens (Human)
Description:
ChEMBL_530099
Residue:
227
Sequence:
MAHAAQVGLQDATSPIMEELITFHDHALMIIFLICFLVLYALFLTLTTKLTNTNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEVNDPSLTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL
  
Inhibitor
Name:
BDBM50595004
Synonyms:
CHEMBL5197349
Type:
Small organic molecule
Emp. Form.:
C27H19ClO5
Mol. Mass.:
458.89
SMILES:
COc1cc(OC)cc(\C=C\c2cc(=O)oc3c4cc(oc4ccc23)-c2cccc(Cl)c2)c1
Structure:
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