Reaction Details Report a problem with these data
Target
P2Y purinoceptor 14
Ligand
BDBM50596027
Substrate
n/a
Meas. Tech.
ChEMBL_2218979 (CHEMBL5132313)
IC50
35±n/a nM
Citation
 Zhou, M; Wang, W; Wang, Z; Wang, Y; Zhu, Y; Lin, Z; Tian, S; Huang, Y; Hu, Q; Li, H Discovery and computational studies of 2-phenyl-benzoxazole acetamide derivatives as promising P2Y Eur J Med Chem 227:0 (2022) [PubMed] 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50596027
Synonyms:
CHEMBL5175099
Type:
Small organic molecule
Emp. Form.:
C23H17F3N2O2
Mol. Mass.:
410.3885
SMILES:
Cc1ccc2oc(nc2c1)-c1cccc(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1
Structure:
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