Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50173186
Substrate
n/a
Meas. Tech.
ChEMBL_320961 (CHEMBL885368)
Ki
120±n/a nM
Citation
 Dowling, JE; Vessels, JT; Haque, S; Chang, HX; van Vloten, K; Kumaravel, G; Engber, T; Jin, X; Phadke, D; Wang, J; Ayyub, E; Petter, RC Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists. Bioorg Med Chem Lett 15:4809-13 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50173186
Synonyms:
8-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyrazine-6-carboxylic acid butylamide | CHEMBL426821
Type:
Small organic molecule
Emp. Form.:
C14H16N6O2
Mol. Mass.:
300.3158
SMILES:
CCCCNC(=O)c1cn2nc(nc2c(N)n1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: