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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50602073
Substrate
n/a
Meas. Tech.
ChEMBL_2239097 (CHEMBL5152993)
EC50
>10000±n/a nM
Citation
 Sato, A; Imashiro, R; Tsujishima, H; Tanimoto, K; Miyashiro, M; Chiba, H; Kondo, M; Yamamoto, Y Discovery of novel N-(1-benzyl-1H-imidazol-2-yl)amide derivatives as melanocortin 1 receptor agonists. Bioorg Med Chem Lett 78:0 (2022) [PubMed] 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50602073
Synonyms:
CHEMBL5204645
Type:
Small organic molecule
Emp. Form.:
C23H26F2N4O
Mol. Mass.:
412.4755
SMILES:
Cn1c(NC(=O)[C@@H]2CN(C[C@H]2c2ccc(F)cc2F)C(C)(C)C)nc2ccccc12 |r|
Structure:
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