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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50602078
Substrate
n/a
Meas. Tech.
ChEMBL_2239097 (CHEMBL5152993)
EC50
339±n/a nM
Citation
 Sato, A; Imashiro, R; Tsujishima, H; Tanimoto, K; Miyashiro, M; Chiba, H; Kondo, M; Yamamoto, Y Discovery of novel N-(1-benzyl-1H-imidazol-2-yl)amide derivatives as melanocortin 1 receptor agonists. Bioorg Med Chem Lett 78:0 (2022) [PubMed] 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50602078
Synonyms:
CHEMBL5181408
Type:
Small organic molecule
Emp. Form.:
C30H38ClF2N5O
Mol. Mass.:
558.105
SMILES:
Cl.CC(C)(C)N1C[C@H]([C@@H](C1)c1ccc(F)cc1F)C(=O)Nc1nccn1Cc1ccccc1N1CCCCC1 |r|
Structure:
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