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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50305261
Substrate
n/a
Meas. Tech.
ChEMBL_2260966 (CHEMBL5215977)
Ki
8.0±n/a nM
Citation
 Kucwaj-Brysz, K; Baltrukevich, H; Czarnota, K; Handzlik, J Chemical update on the potential for serotonin 5-HT Bioorg Med Chem Lett 49:0 (2021) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50305261
Synonyms:
CHEMBL589390 | Dimebolin
Type:
Small organic molecule
Emp. Form.:
C21H25N3
Mol. Mass.:
319.4433
SMILES:
CN1CCc2c(C1)c1cc(C)ccc1n2CCc1ccc(C)nc1
Structure:
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