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Target
D(3) dopamine receptor
Ligand
BDBM50056443
Substrate
n/a
Meas. Tech.
ChEMBL_2269128
Ki
6330±n/a nM
Citation
 Battiti, FO; Zaidi, SA; Katritch, V; Newman, AH; Bonifazi, A Chiral Cyclic Aliphatic Linkers as Building Blocks for Selective Dopamine D J Med Chem 64:16088-16105 (2021) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50056443
Synonyms:
(R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one | CHEMBL419792 | PNU-95666E
Type:
Small organic molecule
Emp. Form.:
C11H13N3O
Mol. Mass.:
203.2404
SMILES:
CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23
Structure:
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