Reaction Details Report a problem with these data
Target
Apoptosis regulator BAX
Ligand
BDBM50610528
Substrate
n/a
Meas. Tech.
ChEMBL_2281425
Kd
15000±n/a nM
Citation
 Pogmore, JP; Uehling, D; Andrews, DW Pharmacological Targeting of Executioner Proteins: Controlling Life and Death. J Med Chem 64:5276-5290 (2021) [PubMed] 
Target
Name:
Apoptosis regulator BAX
Synonyms:
Apoptosis regulator BAX | BAX | BAX_HUMAN | BCL2L4 | Bcl-2-like protein 4 | Bcl2-L-4
Type:
PROTEIN
Mol. Mass.:
21181.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_100916
Residue:
192
Sequence:
MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG
  
Inhibitor
Name:
BDBM50610528
Synonyms:
CHEMBL5289201
Type:
Small organic molecule
Emp. Form.:
C19H20Br2N4O3
Mol. Mass.:
512.195
SMILES:
OC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)c(cc12)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: