Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50199967
Substrate
n/a
Meas. Tech.
ChEMBL_422428 (CHEMBL909840)
Ki
1.4±n/a nM
Citation
 Cosyn, L; Palaniappan, KK; Kim, SK; Duong, HT; Gao, ZG; Jacobson, KA; Van Calenbergh, S 2-triazole-substituted adenosines: a new class of selective A3 adenosine receptor agonists, partial agonists, and antagonists. J Med Chem 49:7373-83 (2006) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50199967
Synonyms:
2-azido-N6-(5-chloro-2-methoxybenzyl)-9-(beta-D-ribofuranosyl)adenine | CHEMBL386698
Type:
Small organic molecule
Emp. Form.:
C18H19ClN8O5
Mol. Mass.:
462.847
SMILES:
COc1ccc(Cl)c(CNc2nc(N=[N+]=[N-])nc3n(cnc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1 |r|
Structure:
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